{"id":404,"date":"2015-08-28T07:28:41","date_gmt":"2015-08-28T04:28:41","guid":{"rendered":"http:\/\/kusuaks7\/?p=9"},"modified":"2024-09-23T10:29:45","modified_gmt":"2024-09-23T10:29:45","slug":"intersection-genomics-big-data","status":"publish","type":"post","link":"https:\/\/www.experfy.com\/blog\/software-ux-ui\/intersection-genomics-big-data\/","title":{"rendered":"The Intersection of Genomics and Big Data"},"content":{"rendered":"\t\t
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\n\t\t\t\t\t\t\t\t\tGenomics\u00a0happens to be the study of the complete genetic material<\/em> of organisms. \u00a0This specialized field of study encompasses the activities related to the sequencing, mapping, and analysis of a wide range of RNA and DNA codes\u0097collected from living organisms spanning the entire hierarchy of the biological kingdom.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tIn the recent years, a lot of focus has been given to determining the entire DNA sequence of humans to understand the gene science present in the human bodies. The primary objective of this intense study is to demystify the correlation between genes and heredity, more specifically heritable traits, so that this knowledge can be put to the beneficial use of disease prevention and cure.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tThe vast amount of data outpours from genome sequencing, mapping, and analyzing has necessitated this scientific field to embrace big data technologies. According to healthcare market analyst, Dr. Bonnie Feldman, Genomics produces huge volumes of data; each human genome has 20,000-25,000 genes comprised of 3 million base pairs. This amounts to\u00a0100 gigabytes of data, equivalent to 102,400 photos<\/a>.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tThus, the routine procedures in Genomics can easily produce petabytes of data with the possibility of further data explosion after gene analysis.\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tAngelina Jolie’s double mastectomy not only fueled widespread public interest in the power of gene science in predicting diseases in human bodies, but also aroused public awareness of the use of genetic data in preventing diseases in future. The importance of big data analytics in Genomics lies in its ability to accumulate and analyze useful gene-related information that can be converted into highly valuable medical insights for disease prevention and cure.\u00a0<\/strong>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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The ongoing research of human genome<\/strong>\u00a0<\/strong><\/h3>\n<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tThe study of human genome dates back to 1990, which saw the initiation of the study and later, pioneered the automated gene-sequencing process.\u00a0 Supported by strong technological advances, the \u00a0Genome Wide Association Studies (GWAS)\u00a0has broadened the scope of their initial study to explore hidden connections between genes and diseases.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tWithout going into the scientific details which you can find in the GWAS site, it is probably useful to state that about 1600 genome studies have established the connected between 2000 gene associations and more than\u00a0300 common human disease traits<\/a>.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tThe current applications that GWAS is engaged with are:\n
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  • Predictive models to identify patients, who may be considered high-risk for a particular type of disease such as Type 1 Diabetes.<\/li>\n \t
  • Classifying disease subtypes for guided clinical trials or targeted treatments of diseases like cancer.<\/li>\n \t
  • High-quality information for screening drug candidates for toxicity and efficacy before clinical trials.<\/li>\n<\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    Genome study inevitable for predictive and preventive medicine<\/strong><\/h3>\n<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    \n\t\t\t\t\t\t\t\t\tGenome study\u0097a study of individual human genome\u0097is the basic foundation for both predictive and preventive medicine<\/em>. With a patient\u0092s genetic data, physicians and researchers can get a clearer grasp diseases or the medical condition of an individual. The other expectation from genome study is that it will enable completely individualized treatments for patients, based on their individual genome data.\u00a0<\/strong>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    The benefit of big data: Drastic cost reduction in genome study<\/strong><\/h3><\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    \n\t\t\t\t\t\t\t\t\tJust a few years ago, the cost of human genome sequencing was $95 million; today it may be less than $ 40 million\u0097and this cost is expected to fall further. \u00a0The research community and the industry, both have been working towards making genome sequencing affordable and accessible to the general public.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    \n\t\t\t\t\t\t\t\t\tToday, individual human genome\u00a0sequencing costs $5000. To better understand the role of big data in Genomics, we recommend\u00a0this video: Genomics, big data, bioinformatics, and the tools necessary to move personalized medicine.<\/strong>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    Genomics\u00a0happens to be the study of the complete genetic material of organisms. \u00a0This specialized field of study encompasses the<\/p>\n","protected":false},"author":11,"featured_media":14652,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"content-type":"","footnotes":""},"categories":[200],"tags":[138],"ppma_author":[1606],"class_list":["post-404","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-software-ux-ui","tag-pharma-and-life-sciences-analytics"],"authors":[{"term_id":1606,"user_id":11,"is_guest":0,"slug":"cameron-turner","display_name":"Cameron Turner","avatar_url":{"url":"https:\/\/www.experfy.com\/blog\/wp-content\/uploads\/2024\/09\/cameron.jpeg","url2x":"https:\/\/www.experfy.com\/blog\/wp-content\/uploads\/2024\/09\/cameron.jpeg"},"user_url":"","last_name":"Turner","first_name":"Cameron","job_title":"","description":""}],"_links":{"self":[{"href":"https:\/\/www.experfy.com\/blog\/wp-json\/wp\/v2\/posts\/404","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.experfy.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.experfy.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.experfy.com\/blog\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/www.experfy.com\/blog\/wp-json\/wp\/v2\/comments?post=404"}],"version-history":[{"count":4,"href":"https:\/\/www.experfy.com\/blog\/wp-json\/wp\/v2\/posts\/404\/revisions"}],"predecessor-version":[{"id":36998,"href":"https:\/\/www.experfy.com\/blog\/wp-json\/wp\/v2\/posts\/404\/revisions\/36998"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.experfy.com\/blog\/wp-json\/wp\/v2\/media\/14652"}],"wp:attachment":[{"href":"https:\/\/www.experfy.com\/blog\/wp-json\/wp\/v2\/media?parent=404"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.experfy.com\/blog\/wp-json\/wp\/v2\/categories?post=404"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.experfy.com\/blog\/wp-json\/wp\/v2\/tags?post=404"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/www.experfy.com\/blog\/wp-json\/wp\/v2\/ppma_author?post=404"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}